L2-2_DRe (DF0003820)

Non-LTR retrotransposon from zebrafish


Reclassified to L2 and renamed. L2-2_DR is a family of L2-like non-LTR retrotransposons and it was active in zebrafish recently. The consensus sequence was reconstructed based on 10 copies that are ~2% divergent from it. Over 7,000 matchtes to L2-2_DR are reported in the zebrafish genome. The consensus sequence encodes only a pol protein (position 1111-4005). A 5'-terminal 1110-bp non-coding is present in L2-2_DR instead of an L2-like ORF1. The 965-aa pol protein is composed of AP endonuclease and reverse transcriptase domains. Endonuclease/reverse transcriptase proteins encoded by L2-2_DR-like elements were probably involved in proliferation of SINE_DR1. L2-2_DR and SINE_DR1 share nearly identical 60-bp 3' tails.


  1. SINEs and LINEs share common 3' sequences: a review.
    Okada N, Hamada M, Ogiwara I, Ohshima K;
    Gene 1997;205:229-243. Pubmed


Accession Name Wikipedia
Type Retrotransposon Article
Class LINE
Superfamily L2

Hit Statistics

The model is 4238 positions long. The average length of non-redundant hits to the model is 694.1. This table shows the number of hits above score thresholds:

Species Gathering Trusted
non-redundant all hits non-redundant all hits
Danio rerio 5857 18013 5348 12104

External Database Links

  • Repbase : L2-2_DRe [Requires Repbase registration]