Harbinger1_DR (DF0003232)

Autonomous Harbinger DNA transposon from zebrafish

Description

HARBINGER1_DR is an autonomous Harbinger-like DNA transposon. Given well preserved 16-bp TIRs, the TAA target site duplication, and encoded protein sequences, HARBINGER1_DR was active in the zebrafish genome recently. The zebrafish genome harbors multiple families of nonautonomous DNA transposons, for example HARBINGERN1_DR, that are derivates of autonomous HARBINGER1_DR-like elements. HARBINGER1_DR encodes two proteins, a 424-aa DNA transposase (2 exons, positions 190-419 and 1084-2128) and a 250-aa DNA-binding protein with the trihelix motif (positions 4001-3249). The latter is related to multiple DNA binding proteins and transcription factors identified in plants (GT-1 proteins), insects (GenBank, g7294624) and mammals (GenBank, g12844693). Presumably, the second protein is a former host gene captured by Harbinger in the past.

Classification

Accession Name Wikipedia
Type DNA Transposon Article
Class Cut and Paste
Superfamily PIF-Harbinger

Hit Statistics

The model is 4016 positions long. The average length of non-redundant hits to the model is 229.6. This table shows the number of hits above score thresholds:

Species Gathering Trusted
non-redundant all hits non-redundant all hits
Danio rerio 410 16581 308 13311

External Database Links