Chapaev-1_CE (DF0001399)

Autonomous DNA transposon

Description

Chapaev-1_CE is a very young family of DNA transposons. The genome contains two identical copies of Chapaev-1_CE and two copies that are 0.5% divergent from the consensus. Chapaev-1_CE belongs to the Chapaev superfamily. Hallmarks of the Chapaev transposons are 4-bp target-site duplications, terminal inverted repeats with the conserved '5-CAC and GTG-3' termini, and the Chapaev transposase. The Chapaev transposase is characterized by the conserved D-x(60-80)-D-x(220-290)-E catalytic triad. Chapaev transposons populate genomes of different animals, including sea urchin Strongylocentrotus purpuratus, amphioxus Branchiostoma floridae, starlet sea anemone Nematostella vectensis, sea hare mollusc Aplysia californica, mosquitoes Aedes aegypti and Culex pipiens, and nematode Caenorhabditis elegans. The N-terminal portion of Chapaev transposase in Chapaev-1_ACa, Chapaev-2_ACa, Chapaev-3_ACa, Chapaev-1_BF, Chapaev-2_BF, Chapaev-1_NV, Chapaev-2_NV, Chapaev-3_NV, and Chapaev-1_SP is similar to the N-terminal portion of RAG1 (100-370 aa in the human RAG1). It includes a novel type of zinc finger, called Chapa: H-X7-C-R-X-C-G-X35-D-X4-H-X4-C-X2-C-W-Xn-C-X2-C-X8-G. In the amphioxus and anemone Chapaevs, the N-terminal portion contains also the RING finger motif. Some Chapaev transposases (e.g. Chapaev-2_ACa) show low similarity to the RAG1 core.

Classification

Accession Name Wikipedia
Type DNA Transposon Article
Class Cut and Paste
Superfamily CMC-Chapaev

Hit Statistics

The model is 4753 positions long. The average length of non-redundant hits to the model is 460.2. This table shows the number of hits above score thresholds:

Species Gathering Trusted
non-redundant all hits non-redundant all hits
Caenorhabditis elegans 74 245 56 127

External Database Links