MER123 (DF0000720)

Unclassified, palindromic DNA transposon, MER123 subfamily

Description

MER123 forms a hairpin-like structure suggesting an ancient DNA transposon preserved in very diverged organisms. It may have a biological function. MER123 forms a near-perfect palindrome, and is conserved in mammals, birds, lizards and in at least one position in Xenopus. Note that MER stands for MEdium Reiteration frequency interspersed repeat. As such, MERs as a group are a grab bag of DNA transposons and retrotransposons.

References

  1. Evolutionary dynamics of transposable elements in the short-tailed opossum Monodelphis domestica.
    Gentles AJ, Wakefield MJ, Kohany O, Gu W, Batzer MA, Pollock DD, Jurka J;
    Genome Res 2007;17:992-1004 Pubmed

  2. Repetitive sequences in complex genomes: structure and evolution.
    Jurka J, Kapitonov VV, Kohany O, Jurka MV;
    Annu Rev Genomics Hum Genet 2007;8:241-259 Pubmed

Classification

Accession Name Wikipedia
Type DNA Transposon Article
Class Cut and Paste
Superfamily Undefined

Hit Statistics

The model is 265 positions long. The average length of non-redundant hits to the model is 197.2. This table shows the number of hits above score thresholds:

Species Gathering Trusted
non-redundant all hits non-redundant all hits
Mus musculus 49 91 33 63
Homo sapiens 62 122 46 89

External Database Links