LSAU (Long Sau3a) satellite DNA, associated with beta satellite
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LSAU reflects some of the flanking sequence surrounding the segmentally-duplicated DUX (double homeobox) genes. LSAU was orginally considered to be satellite DNA, observed to be associated with beta-satellite DNA. The DUX gene repeat is not always associated with beta-satellite.
The DNA rearrangement associated with facioscapulohumeral muscular dystrophy involves a heterochromatin-associated repetitive element: implications for a role of chromatin structure in the pathogenesis of the disease.
Winokur ST, Bengtsson U, Feddersen J, Mathews KD, Weiffenbach B, Bailey H, Markovich RP, Murray JC, Wasmuth JJ, Altherr MR;
Chromosome Res 1994;2:225-234 Pubmed
Molecular organization and chromosomal location of human GC-rich heterochromatic blocks.
Meneveri R, Agresti A, Marozzi A, Saccone S, Rocchi M, Archidiacono N, Corneo G, Della Valle G, Ginelli E;
Gene 1993;123:227-234 Pubmed
Number of matches to this model that meet the "Gathering" threshold and more stringent "Trusted" threshold. For each threshold, two numbers are shown: (1) the number of matches to this model after removing redundant hits to other models ("non-redundant"), and (2) the total number of matches above threshold, including those with better scoring matches to other models ("all hits").
The model is 498 positions long. The average length of non-redundant hits to the model is 286.2. This table shows the number of hits above score thresholds:
|non-redundant||all hits||non-redundant||all hits|