L2 (DF0000358)

L2 (LINE2) retrotransposon


L2 (LINE2) spread before the mammalian radiation, and copies are only 65-75% similar to the consensus. The 5' end is probably incomplete. The 3' end is also incomplete, but this terminus is extended by three model variants: L2a_3end, L2b_3end, and L2c_3end. Note that, whereas L1 is A- and purine-rich in the coding strand, L2 is C- and pyrimidine-rich.


  1. Nucleotide sequence of the gene for human prothrombin.
    Degen SJ, Davie EW;
    Biochemistry 1987;26:6165-6177 Pubmed

  2. MIRs are classic, tRNA-derived SINEs that amplified before the mammalian radiation.
    Smit AF, Riggs AD;
    Nucleic Acids Res 1995;23:98-102 Pubmed


Accession Name Wikipedia
Type Retrotransposon Article
Class LINE
Superfamily L2

Hit Statistics

The model is 3082 positions long. The average length of non-redundant hits to the model is 398.3. This table shows the number of hits above score thresholds:

Species Gathering Trusted
non-redundant all hits non-redundant all hits
Mus musculus 19298 28180 7786 10421
Homo sapiens 100361 199525 64986 116498

External Database Links

  • Repbase : L2 [Requires Repbase registration]