HERVK14 (DF0000192)

Internal region of ERVK endogenous retrovirus, HERVK14 subfamily

Description

Human HERV-K14 and its variants were examined carefully by Flockerzi et al [2]. HERVK14 is found both with and without an env gene. This model lacks an env. In the rare variants that do, env would start around position 5144. Long terminal repeats associated with HERVK14 are LTR14A and LTR14B. Features in the consensus from ref [2]: lysine PBS (~9-28), gag (~125-1798), protease (~1657-2604), pol (~2535-5183), polypyrimidine tract (~6078-6095).

Synonyms: HERV-K14I

References

  1. Characterization of novel reverse transcriptase encoding human endogenous retroviral sequences similar to type A and type B retroviruses: differential transcription in normal human tissues.
    Medstrand P, Blomberg J;
    J Virol 1993;67:6778-6787 Pubmed

  2. Human endogenous retrovirus HERV-K14 families: status, variants, evolution, and mobilization of other cellular sequences.
    Flockerzi A, Burkhardt S, Schempp W, Meese E, Mayer J;
    J Virol 2005;79:2941-2949 Pubmed

Classification

Accession Name Wikipedia
Type Retrotransposon Article
Class LTR Article
Superfamily ERVK Article

Hit Statistics

The model is 6096 positions long. The average length of non-redundant hits to the model is 774.7. This table shows the number of hits above score thresholds:

Species Gathering Trusted
non-redundant all hits non-redundant all hits
Homo sapiens 331 3071 264 2325

External Database Links

  • Repbase : HERV-K14I [Requires Repbase registration]