HERVIP10F (DF0000186)

Internal region of ERV1 endogenous retrovirus, HERVIP10F subfamily


HERVIP10F is flanked by LTR10F long terminal repeats; these have 5 bp TSDs. HERVIP10F was an active endogenous retrovirus ~30 Myr ago. There are about 20 copies of the HERVIP10F internal sequence present in the human genome (not the same as a simply tally of fragmented hits). Three ORFs are found in the HERVIP10F consensus. ORF1 encodes gagP71A (~504-2216), a 571aa gag-like protein, closely related to gag proteins encoded by the C-type leukemia retroviruses. ORF2 encodes polIP10F (~2220-5720), an 1167aa polyprotein composed of protease (140aa), reverse transcriptase (517aa), RNase H (140aa) and endonuclease (270aa) domains, respectively. ORF3 encodes envIP10F (~5621-7735), a 705aa and envelope protein most similar to those from leukemia retroviruses.


Accession Name Wikipedia
Type Retrotransposon Article
Class LTR Article
Superfamily ERV1 Article

Hit Statistics

The model is 7737 positions long. The average length of non-redundant hits to the model is 1417.9. This table shows the number of hits above score thresholds:

Species Gathering Trusted
non-redundant all hits non-redundant all hits
Homo sapiens 342 7814 327 5548

External Database Links

  • Repbase : HERVIP10F [Requires Repbase registration]