Internal region of an ERV1 endogenous retrovirus, HERVE subfamily
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Associated long terminal repeat is LTR2. The gag and pol genes are ~40% similar to Moloney murine leukemia virus (MoMuLV). Some unique characteristics of the endogenous human retroviral DNA included a tRNA Glu primer binding site separated from the 5' LTR by a pentanucleotide and a putative env sequence which does not appear to overlap the C terminus of pol and has virtually no homology with the env gene of known infectious retroviruses. The reconstructed (though still pseudogenic) gene boundaries are: Gag: 571-2094, Pol: 2095-5655, Env: 5678-7750.
Distinctive termini characterize two families of human endogenous retroviral sequences.
Steele PE, Rabson AB, Bryan T, Martin MA;
Science 1984;225:943-947 Pubmed
Nucleotide sequence of a full-length human endogenous retroviral segment.
Repaske R, Steele PE, O'Neill RR, Rabson AB, Martin MA;
J Virol 1985;54:764-772 Pubmed
Number of matches to this model that meet the "Gathering" threshold and more stringent "Trusted" threshold. For each threshold, two numbers are shown: (1) the number of matches to this model after removing redundant hits to other models ("non-redundant"), and (2) the total number of matches above threshold, including those with better scoring matches to other models ("all hits").
The model is 7813 positions long. The average length of non-redundant hits to the model is 2279.2. This table shows the number of hits above score thresholds:
|non-redundant||all hits||non-redundant||all hits|
External Database Links
- Repbase : HERVE [Requires Repbase registration]