MIR (Mammalian-wide Interspersed Repeat)
A brief description of the entry. Suggestions for modification to this description can be submitted using the adjacent pencil icon.
MIR is a pan-mammalian SINE with a 5' end derived from a tRNA, a central deeply-conserved CORE region , and a 3' terminal ~55bp related to an L2 LINE.
Nucleotide sequence of the gene for human prothrombin.
Degen SJ, Davie EW;
Biochemistry 1987;26:6165-6177 Pubmed
Identification of a conserved sequence in the noncoding regions of many human genes.
Donehower LA, Slagle BL, Wilde M, Darlington G, Butel JS;
Nucleic Acids Res 1989;17:699-710 Pubmed
Ubiquitous mammalian-wide interspersed repeats (MIRs) are molecular fossils from the mesozoic era.
Jurka J, Zietkiewicz E, Labuda D;
Nucleic Acids Res 1995;23:170-175 Pubmed
MIRs are classic, tRNA-derived SINEs that amplified before the mammalian radiation.
Smit AF, Riggs AD;
Nucleic Acids Res 1995;23:98-102 Pubmed
Evolutionary inventions and continuity of CORE-SINEs in mammals.
Gilbert N, Labuda D;
J Mol Biol 2000;298:365-377 Pubmed
Number of matches to this model that meet the "Gathering" threshold and more stringent "Trusted" threshold. For each threshold, two numbers are shown: (1) the number of matches to this model after removing redundant hits to other models ("non-redundant"), and (2) the total number of matches above threshold, including those with better scoring matches to other models ("all hits").
The model is 262 positions long. The average length of non-redundant hits to the model is 187.2. This table shows the number of hits above score thresholds:
|non-redundant||all hits||non-redundant||all hits|
External Database Links
- Repbase : MIR [Requires Repbase registration]