MIR (DF0000001)

MIR (Mammalian-wide Interspersed Repeat)

Description

MIR is a pan-mammalian SINE with a 5' end derived from a tRNA, a central deeply-conserved CORE region [5], and a 3' terminal ~55bp related to an L2 LINE.

References

  1. Nucleotide sequence of the gene for human prothrombin.
    Degen SJ, Davie EW;
    Biochemistry 1987;26:6165-6177 Pubmed

  2. Identification of a conserved sequence in the noncoding regions of many human genes.
    Donehower LA, Slagle BL, Wilde M, Darlington G, Butel JS;
    Nucleic Acids Res 1989;17:699-710 Pubmed

  3. Ubiquitous mammalian-wide interspersed repeats (MIRs) are molecular fossils from the mesozoic era.
    Jurka J, Zietkiewicz E, Labuda D;
    Nucleic Acids Res 1995;23:170-175 Pubmed

  4. MIRs are classic, tRNA-derived SINEs that amplified before the mammalian radiation.
    Smit AF, Riggs AD;
    Nucleic Acids Res 1995;23:98-102 Pubmed

  5. Evolutionary inventions and continuity of CORE-SINEs in mammals.
    Gilbert N, Labuda D;
    J Mol Biol 2000;298:365-377 Pubmed

Classification

Accession Name Wikipedia
Type Retrotransposon Article
Class SINE
Superfamily MIR

Hit Statistics

The model is 262 positions long. The average length of non-redundant hits to the model is 187.2. This table shows the number of hits above score thresholds:

Species Gathering Trusted
non-redundant all hits non-redundant all hits
Mus musculus 39821 156938 12404 24303
Homo sapiens 139914 569017 106052 290706

External Database Links

  • Repbase : MIR [Requires Repbase registration]